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Brief isoflurane anesthesia regulates striatal AKT‐GSK3β signaling and ameliorates motor deficits in a rat model of early‐stage Parkinson′s disease

Parkinson's disease (PD) is a progressive neurodegenerative movement disorder primarily affecting the nigrostriatal dopaminergic system. The link between heightened activity of glycogen synthase kinase 3β (GSK3β) and neurodegene‐rative processes has encouraged investigation into the potential d...

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Detalles Bibliográficos
Autores principales: Leikas, Juuso V., Kohtala, Samuel, Theilmann, Wiebke, Jalkanen, Aaro J., Forsberg, Markus M., Rantamäki, Tomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575520/
https://www.ncbi.nlm.nih.gov/pubmed/28488766
http://dx.doi.org/10.1111/jnc.14066