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Brief isoflurane anesthesia regulates striatal AKT‐GSK3β signaling and ameliorates motor deficits in a rat model of early‐stage Parkinson′s disease
Parkinson's disease (PD) is a progressive neurodegenerative movement disorder primarily affecting the nigrostriatal dopaminergic system. The link between heightened activity of glycogen synthase kinase 3β (GSK3β) and neurodegene‐rative processes has encouraged investigation into the potential d...
Autores principales: | Leikas, Juuso V., Kohtala, Samuel, Theilmann, Wiebke, Jalkanen, Aaro J., Forsberg, Markus M., Rantamäki, Tomi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575520/ https://www.ncbi.nlm.nih.gov/pubmed/28488766 http://dx.doi.org/10.1111/jnc.14066 |
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