Novel compounds targeting the enterohemorrhagic Escherichia coli type three secretion system reveal insights into mechanisms of secretion inhibition

Anti‐virulence (AV) compounds are a promising alternative to traditional antibiotics for fighting bacterial infections. The Type Three Secretion System (T3SS) is a well‐studied and attractive AV target, given that it is widespread in more than 25 species of Gram‐negative bacteria, including enterohe...

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Detalles Bibliográficos
Autores principales: Zambelloni, Riccardo, Connolly, James P.R., Huerta Uribe, Alejandro, Burgess, Karl, Marquez, Rodolfo, Roe, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575525/
https://www.ncbi.nlm.nih.gov/pubmed/28557017
http://dx.doi.org/10.1111/mmi.13719

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