Impact of Larger Sputum Volume on Xpert(®) MTB/RIF Assay Detection of Mycobacterium tuberculosis in Smear-Negative Individuals with Suspected Tuberculosis

As a strategy to improve the sensitivity of nucleic acid-based testing in acid-fast bacilli (AFB) negative samples, larger volumes of sputum (5–10 mL) were tested with Xpert(®) MTB/RIF from 176 individuals with smear-negative sputum undergoing tuberculosis evaluation. Despite larger volumes, this st...

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Detalles Bibliográficos
Autores principales: Badal-Faesen, Sharlaa, Firnhaber, Cynthia, Kendall, Michelle A., Wu, Xingye, Grinsztejn, Beatriz, Escada, Rodrigo Otavio da Silva, Fernandez, Michel, Hogg, Evelyn, Sanne, Ian, Johnson, Pamela, Alland, David, Mazurek, Gerald H., Benator, Debra A., Luetkemeyer, Anne F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575580/
https://www.ncbi.nlm.nih.gov/pubmed/28783093
http://dx.doi.org/10.3390/jcm6080078

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