Cargando…

Use of FGF-21 as a Biomarker of Mitochondrial Disease in Clinical Practice

Recent work has suggested that fibroblast growth factor-21 (FGF-21) is a useful biomarker of mitochondrial disease (MD). We routinely measured FGF-21 levels on patients who were investigated at our centre for MD and evaluated its diagnostic performance based on detailed genetic and other laboratory...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morovat, Alireza, Weerasinghe, Gayani, Nesbitt, Victoria, Hofer, Monika, Agnew, Thomas, Quaghebeur, Geralrine, Sergeant, Kate, Fratter, Carl, Guha, Nishan, Mirzazadeh, Mehdi, Poulton, Joanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575582/ https://www.ncbi.nlm.nih.gov/pubmed/28825656 http://dx.doi.org/10.3390/jcm6080080

Ejemplares similares

Clinical features of the pathogenic m.5540G>A mitochondrial transfer RNA tryptophan gene mutation
por: Ng, Yi Shiau, et al.
Publicado: (2016)

UK Reference Intervals for Parathyroid Hormone Using Abbott Methods
por: Mirzazadeh, Mehdi, et al.
Publicado: (2023)

FGF19 subfamily members: FGF19 and FGF21
por: Dolegowska, Katarzyna, et al.
Publicado: (2019)

De novo DNM1L mutation associated with mitochondrial epilepsy syndrome with fever sensitivity
por: Ladds, Emma, et al.
Publicado: (2018)

A national perspective on prenatal testing for mitochondrial disease
por: Nesbitt, Victoria, et al.
Publicado: (2014)

FGF19 and FGF21: In NASH we trust
por: Talukdar, Saswata, et al.
Publicado: (2020)

FGF21 and Cardiac Physiopathology
por: Planavila, Anna, et al.
Publicado: (2015)

Fundamentals of FGF19 & FGF21 Action In Vitro and In Vivo
por: Adams, Andrew C., et al.
Publicado: (2012)

FGF19 and FGF21 for the Treatment of NASH—Two Sides of the Same Coin? Differential and Overlapping Effects of FGF19 and FGF21 From Mice to Human
por: Henriksson, Emma, et al.
Publicado: (2020)

Aging is associated with increased FGF21 levels but unaltered FGF21 responsiveness in adipose tissue
por: Villarroya, Joan, et al.
Publicado: (2018)

Fibroblast Growth Factor 21 (FGF21) in Human Cerebrospinal Fluid: Relationship With Plasma FGF21 and Body Adiposity
por: Tan, Bee K., et al.
Publicado: (2011)

FGF21 as a Stress Hormone: The Roles of FGF21 in Stress Adaptation and the Treatment of Metabolic Diseases
por: Kim, Kook Hwan, et al.
Publicado: (2014)

Pitfalls of relying on genetic testing only to diagnose inherited metabolic disorders in non-western populations - 5 cases of pyruvate dehydrogenase deficiency from South Africa
por: Meldau, Surita, et al.
Publicado: (2020)

Head Over Hepatocytes for FGF21
por: Potthoff, Matthew J., et al.
Publicado: (2014)

Analysis of Functional Promoter of Camel FGF21 Gene and Identification of Small Compounds Targeting FGF21 Protein
por: Yong, Fang, et al.
Publicado: (2023)

Lower Cerebrospinal Fluid/Plasma Fibroblast Growth Factor 21 (FGF21) Ratios and Placental FGF21 Production in Gestational Diabetes
por: Tan, Bee K., et al.
Publicado: (2013)

The Suitability of FGF21 and FGF23 as New Biomarkers in Endometrial Cancer Patients
por: Cymbaluk-Płoska, Aneta, et al.
Publicado: (2020)

Biological and pharmacological functions of the FGF19- and FGF21-coreceptor beta klotho
por: Aaldijk, Alexandra S., et al.
Publicado: (2023)

Paradoxical Regulation of Human FGF21 by Both Fasting and Feeding Signals: Is FGF21 a Nutritional Adaptation Factor?
por: Uebanso, Takashi, et al.
Publicado: (2011)

Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity
por: Agrawal, Archita, et al.
Publicado: (2018)

Association between FGF19, FGF21 and lipocalin-2, and diabetes progression in PCOS
por: Cheng, Feifei, et al.
Publicado: (2021)

Inventing new medicines: The FGF21 story()
por: Kharitonenkov, Alexei, et al.
Publicado: (2013)

The good, the bad, and the unknown: Fructose and FGF21()
por: Hofmann, Susanna M., et al.
Publicado: (2014)

Metabolic Effects of FGF-21: Thermoregulation and Beyond
por: Ni, Bin, et al.
Publicado: (2015)

FGF-21 levels in polyuria-polydipsia syndrome
por: Refardt, Julie, et al.
Publicado: (2018)

FGF21 Levels in Pheochromocytoma/Functional Paraganglioma
por: Klímová, Judita, et al.
Publicado: (2019)

FGF21 as Modulator of Metabolism in Health and Disease
por: Tezze, Caterina, et al.
Publicado: (2019)

FGF21 and the Physiological Regulation of Macronutrient Preference
por: Hill, Cristal M, et al.
Publicado: (2020)

The role of FGF21 in the pathogenesis of cardiovascular disease
por: Zhang, Ying, et al.
Publicado: (2021)

CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms
por: Satoh, Aoi, et al.
Publicado: (2020)

Pathogenic SLC25A26 variants impair SAH transport activity causing mitochondrial disease
por: Rosenberger, Florian A, et al.
Publicado: (2022)

Depletion of mitochondrial DNA in fibroblast cultures from patients with POLG1 mutations is a consequence of catalytic mutations
por: Ashley, Neil, et al.
Publicado: (2008)

FGF21 regulates alcohol intake: New hopes on the rise for alcohol use disorder treatment?
por: Wang, Tammy, et al.
Publicado: (2022)

Exercise Increases Serum Fibroblast Growth Factor 21 (FGF21) Levels
por: Cuevas-Ramos, Daniel, et al.
Publicado: (2012)

Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State
por: Fisher, ffolliott M., et al.
Publicado: (2010)

FGF21 contributes to neuroendocrine control of female reproduction
por: Owen, Bryn M., et al.
Publicado: (2013)

Stressed Liver and Muscle Call on Adipocytes with FGF21
por: Luo, Yongde, et al.
Publicado: (2013)

Metformin Stimulates FGF21 Expression in Primary Hepatocytes
por: Nygaard, Eva B., et al.
Publicado: (2012)

FGF21 Requires βklotho to Act In Vivo
por: Adams, Andrew C., et al.
Publicado: (2012)

FGF21 Is Associated with Acanthosis Nigricans in Obese Patients
por: Huang, Yueye, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_jbifp48spvmv2lq24mrq1js0da