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The Genetic Architecture of Type 1 Diabetes

Type 1 diabetes (T1D) is classically characterised by the clinical need for insulin, the presence of disease-associated serum autoantibodies, and an onset in childhood. The disease, as with other autoimmune diseases, is due to the interaction of genetic and non-genetic effects, which induce a destru...

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Detalles Bibliográficos
Autores principales: Jerram, Samuel T., Leslie, Richard David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5575672/
https://www.ncbi.nlm.nih.gov/pubmed/28829396
http://dx.doi.org/10.3390/genes8080209