PIWI-like protein, HIWI2 is aberrantly expressed in retinoblastoma cells and affects cell-cycle potentially through OTX2

Retinoblastoma (RB), a childhood cancer, is caused by biallelic mutation of the RB1 gene, but its development is not clearly understood. Furthermore, the presence of a cancer stem cell subpopulation in RB might impact its treatment. PIWI protein, known for its role in stem cell self-renewal, is aber...

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Detalles Bibliográficos
Autores principales: Sivagurunathan, Suganya, Arunachalam, Jayamuruga Pandian, Chidambaram, Subbulakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576095/
https://www.ncbi.nlm.nih.gov/pubmed/28861107
http://dx.doi.org/10.1186/s11658-017-0048-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576095/
https://www.ncbi.nlm.nih.gov/pubmed/28861107
http://dx.doi.org/10.1186/s11658-017-0048-y

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