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EGFR copy number alterations in primary tumors, metastatic lymph nodes, and recurrent and multiple primary tumors in oral cavity squamous cell carcinoma

BACKGROUND: The EGFR and downstream signaling pathways play an important role in tumorigenesis in oral squamous cell carcinoma (OSCC). Gene copy number alteration is one mechanism for overexpressing the EGFR protein and was also demonstrated to be related to lymph node metastasis, tumor invasiveness...

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Detalles Bibliográficos
Autores principales:	Huang, Shiang-Fu, Chien, Huei-Tzu, Cheng, Sou-De, Chuang, Wen-Yu, Liao, Chun-Ta, Wang, Hung-Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576106/ https://www.ncbi.nlm.nih.gov/pubmed/28854970 http://dx.doi.org/10.1186/s12885-017-3586-9

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