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Honokiol improved chondrogenesis and suppressed inflammation in human umbilical cord derived mesenchymal stem cells via blocking nuclear factor-κB pathway

BACKGROUND: Cartilage degradation is the significant pathological process in osteoarthritis (OA). Inflammatory cytokines, such as interleukin-1β (IL-1β), activate various downstream mediators contributing to OA pathology. Recently, stem cell-based cartilage repair emerges as a potential therapeutic...

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Detalles Bibliográficos
Autores principales: Wu, Hao, Yin, Zhanhai, Wang, Ling, Li, Feng, Qiu, Yusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576244/
https://www.ncbi.nlm.nih.gov/pubmed/28851291
http://dx.doi.org/10.1186/s12860-017-0145-9