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Dietary arachidonic acid increases deleterious effects of amyloid-β oligomers on learning abilities and expression of AMPA receptors: putative role of the ACSL4-cPLA(2) balance

BACKGROUND: Polyunsaturated fatty acids play a crucial role in neuronal function, and the modification of these compounds in the brain could have an impact on neurodegenerative diseases such as Alzheimer’s disease. Despite the fact that arachidonic acid is the second foremost polyunsaturated fatty a...

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Detalles Bibliográficos
Autores principales: Thomas, Mélanie H., Paris, Cédric, Magnien, Mylène, Colin, Julie, Pelleïeux, Sandra, Coste, Florence, Escanyé, Marie-Christine, Pillot, Thierry, Olivier, Jean-Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576249/
https://www.ncbi.nlm.nih.gov/pubmed/28851448
http://dx.doi.org/10.1186/s13195-017-0295-1

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