REstricted Fluid REsuscitation in Sepsis-associated Hypotension (REFRESH): study protocol for a pilot randomised controlled trial

BACKGROUND: Guidelines recommend an initial intravenous (IV) fluid bolus of 30 ml/kg isotonic crystalloid for patients with sepsis and hypotension. However, there is a lack of evidence from clinical trials to support this. Accumulating observational data suggest harm associated with the injudicious...

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Detalles Bibliográficos
Autores principales: Macdonald, Stephen P. J., Taylor, David McD, Keijzers, Gerben, Arendts, Glenn, Fatovich, Daniel M., Kinnear, Frances B., Brown, Simon G. A., Bellomo, Rinaldo, Burrows, Sally, Fraser, John F., Litton, Edward, Ascencio-Lane, Juan Carlos, Anstey, Matthew, McCutcheon, David, Smart, Lisa, Vlad, Ioana, Winearls, James, Wibrow, Bradley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576288/
https://www.ncbi.nlm.nih.gov/pubmed/28851407
http://dx.doi.org/10.1186/s13063-017-2137-7

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