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Impairments in laterodorsal tegmentum to VTA projections underlie glucocorticoid-triggered reward deficits

Ventral tegmental area (VTA) activity is critical for reward/reinforcement and is tightly modulated by the laterodorsal tegmentum (LDT). In utero exposure to glucocorticoids (iuGC) triggers prominent motivation deficits but nothing is known about the impact of this exposure in the LDT-VTA circuit. W...

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Detalles Bibliográficos
Autores principales: Coimbra, Bárbara, Soares-Cunha, Carina, Borges, Sónia, Vasconcelos, Nivaldo AP, Sousa, Nuno, Rodrigues, Ana João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576484/
https://www.ncbi.nlm.nih.gov/pubmed/28837419
http://dx.doi.org/10.7554/eLife.25843