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Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells

The urokinase receptor (uPAR) is a glycosylphosphatidylinositol (GPI)-anchored protein that promotes tissue remodeling, tumor cell adhesion, migration and invasion. uPAR mediates degradation of the extracellular matrix through protease recruitment and enhances cell adhesion, migration and signaling...

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Detalles Bibliográficos
Autores principales:	van Veen, Michiel, Matas-Rico, Elisa, van de Wetering, Koen, Leyton-Puig, Daniela, Kedziora, Katarzyna M, De Lorenzi, Valentina, Stijf-Bultsma, Yvette, van den Broek, Bram, Jalink, Kees, Sidenius, Nicolai, Perrakis, Anastassis, Moolenaar, Wouter H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576486/ https://www.ncbi.nlm.nih.gov/pubmed/28849762 http://dx.doi.org/10.7554/eLife.23649

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