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Increasing suppression of saccade-related transients along the human visual hierarchy

A key hallmark of visual perceptual awareness is robustness to instabilities arising from unnoticeable eye and eyelid movements. In previous human intracranial (iEEG) work (Golan et al., 2016) we found that excitatory broadband high-frequency activity transients, driven by eye blinks, are suppressed...

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Autores principales: Golan, Tal, Davidesco, Ido, Meshulam, Meir, Groppe, David M, Mégevand, Pierre, Yeagle, Erin M, Goldfinger, Matthew S, Harel, Michal, Melloni, Lucia, Schroeder, Charles E, Deouell, Leon Y, Mehta, Ashesh D, Malach, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576487/
https://www.ncbi.nlm.nih.gov/pubmed/28850030
http://dx.doi.org/10.7554/eLife.27819
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author Golan, Tal
Davidesco, Ido
Meshulam, Meir
Groppe, David M
Mégevand, Pierre
Yeagle, Erin M
Goldfinger, Matthew S
Harel, Michal
Melloni, Lucia
Schroeder, Charles E
Deouell, Leon Y
Mehta, Ashesh D
Malach, Rafael
author_facet Golan, Tal
Davidesco, Ido
Meshulam, Meir
Groppe, David M
Mégevand, Pierre
Yeagle, Erin M
Goldfinger, Matthew S
Harel, Michal
Melloni, Lucia
Schroeder, Charles E
Deouell, Leon Y
Mehta, Ashesh D
Malach, Rafael
author_sort Golan, Tal
collection PubMed
description A key hallmark of visual perceptual awareness is robustness to instabilities arising from unnoticeable eye and eyelid movements. In previous human intracranial (iEEG) work (Golan et al., 2016) we found that excitatory broadband high-frequency activity transients, driven by eye blinks, are suppressed in higher-level but not early visual cortex. Here, we utilized the broad anatomical coverage of iEEG recordings in 12 eye-tracked neurosurgical patients to test whether a similar stabilizing mechanism operates following small saccades. We compared saccades (1.3°−3.7°) initiated during inspection of large individual visual objects with similarly-sized external stimulus displacements. Early visual cortex sites responded with positive transients to both conditions. In contrast, in both dorsal and ventral higher-level sites the response to saccades (but not to external displacements) was suppressed. These findings indicate that early visual cortex is highly unstable compared to higher-level visual regions which apparently constitute the main target of stabilizing extra-retinal oculomotor influences.
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spelling pubmed-55764872017-08-31 Increasing suppression of saccade-related transients along the human visual hierarchy Golan, Tal Davidesco, Ido Meshulam, Meir Groppe, David M Mégevand, Pierre Yeagle, Erin M Goldfinger, Matthew S Harel, Michal Melloni, Lucia Schroeder, Charles E Deouell, Leon Y Mehta, Ashesh D Malach, Rafael eLife Neuroscience A key hallmark of visual perceptual awareness is robustness to instabilities arising from unnoticeable eye and eyelid movements. In previous human intracranial (iEEG) work (Golan et al., 2016) we found that excitatory broadband high-frequency activity transients, driven by eye blinks, are suppressed in higher-level but not early visual cortex. Here, we utilized the broad anatomical coverage of iEEG recordings in 12 eye-tracked neurosurgical patients to test whether a similar stabilizing mechanism operates following small saccades. We compared saccades (1.3°−3.7°) initiated during inspection of large individual visual objects with similarly-sized external stimulus displacements. Early visual cortex sites responded with positive transients to both conditions. In contrast, in both dorsal and ventral higher-level sites the response to saccades (but not to external displacements) was suppressed. These findings indicate that early visual cortex is highly unstable compared to higher-level visual regions which apparently constitute the main target of stabilizing extra-retinal oculomotor influences. eLife Sciences Publications, Ltd 2017-08-29 /pmc/articles/PMC5576487/ /pubmed/28850030 http://dx.doi.org/10.7554/eLife.27819 Text en © 2017, Golan et al http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Neuroscience
Golan, Tal
Davidesco, Ido
Meshulam, Meir
Groppe, David M
Mégevand, Pierre
Yeagle, Erin M
Goldfinger, Matthew S
Harel, Michal
Melloni, Lucia
Schroeder, Charles E
Deouell, Leon Y
Mehta, Ashesh D
Malach, Rafael
Increasing suppression of saccade-related transients along the human visual hierarchy
title Increasing suppression of saccade-related transients along the human visual hierarchy
title_full Increasing suppression of saccade-related transients along the human visual hierarchy
title_fullStr Increasing suppression of saccade-related transients along the human visual hierarchy
title_full_unstemmed Increasing suppression of saccade-related transients along the human visual hierarchy
title_short Increasing suppression of saccade-related transients along the human visual hierarchy
title_sort increasing suppression of saccade-related transients along the human visual hierarchy
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576487/
https://www.ncbi.nlm.nih.gov/pubmed/28850030
http://dx.doi.org/10.7554/eLife.27819
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