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Increasing suppression of saccade-related transients along the human visual hierarchy
A key hallmark of visual perceptual awareness is robustness to instabilities arising from unnoticeable eye and eyelid movements. In previous human intracranial (iEEG) work (Golan et al., 2016) we found that excitatory broadband high-frequency activity transients, driven by eye blinks, are suppressed...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576487/ https://www.ncbi.nlm.nih.gov/pubmed/28850030 http://dx.doi.org/10.7554/eLife.27819 |
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author | Golan, Tal Davidesco, Ido Meshulam, Meir Groppe, David M Mégevand, Pierre Yeagle, Erin M Goldfinger, Matthew S Harel, Michal Melloni, Lucia Schroeder, Charles E Deouell, Leon Y Mehta, Ashesh D Malach, Rafael |
author_facet | Golan, Tal Davidesco, Ido Meshulam, Meir Groppe, David M Mégevand, Pierre Yeagle, Erin M Goldfinger, Matthew S Harel, Michal Melloni, Lucia Schroeder, Charles E Deouell, Leon Y Mehta, Ashesh D Malach, Rafael |
author_sort | Golan, Tal |
collection | PubMed |
description | A key hallmark of visual perceptual awareness is robustness to instabilities arising from unnoticeable eye and eyelid movements. In previous human intracranial (iEEG) work (Golan et al., 2016) we found that excitatory broadband high-frequency activity transients, driven by eye blinks, are suppressed in higher-level but not early visual cortex. Here, we utilized the broad anatomical coverage of iEEG recordings in 12 eye-tracked neurosurgical patients to test whether a similar stabilizing mechanism operates following small saccades. We compared saccades (1.3°−3.7°) initiated during inspection of large individual visual objects with similarly-sized external stimulus displacements. Early visual cortex sites responded with positive transients to both conditions. In contrast, in both dorsal and ventral higher-level sites the response to saccades (but not to external displacements) was suppressed. These findings indicate that early visual cortex is highly unstable compared to higher-level visual regions which apparently constitute the main target of stabilizing extra-retinal oculomotor influences. |
format | Online Article Text |
id | pubmed-5576487 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | eLife Sciences Publications, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-55764872017-08-31 Increasing suppression of saccade-related transients along the human visual hierarchy Golan, Tal Davidesco, Ido Meshulam, Meir Groppe, David M Mégevand, Pierre Yeagle, Erin M Goldfinger, Matthew S Harel, Michal Melloni, Lucia Schroeder, Charles E Deouell, Leon Y Mehta, Ashesh D Malach, Rafael eLife Neuroscience A key hallmark of visual perceptual awareness is robustness to instabilities arising from unnoticeable eye and eyelid movements. In previous human intracranial (iEEG) work (Golan et al., 2016) we found that excitatory broadband high-frequency activity transients, driven by eye blinks, are suppressed in higher-level but not early visual cortex. Here, we utilized the broad anatomical coverage of iEEG recordings in 12 eye-tracked neurosurgical patients to test whether a similar stabilizing mechanism operates following small saccades. We compared saccades (1.3°−3.7°) initiated during inspection of large individual visual objects with similarly-sized external stimulus displacements. Early visual cortex sites responded with positive transients to both conditions. In contrast, in both dorsal and ventral higher-level sites the response to saccades (but not to external displacements) was suppressed. These findings indicate that early visual cortex is highly unstable compared to higher-level visual regions which apparently constitute the main target of stabilizing extra-retinal oculomotor influences. eLife Sciences Publications, Ltd 2017-08-29 /pmc/articles/PMC5576487/ /pubmed/28850030 http://dx.doi.org/10.7554/eLife.27819 Text en © 2017, Golan et al http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Neuroscience Golan, Tal Davidesco, Ido Meshulam, Meir Groppe, David M Mégevand, Pierre Yeagle, Erin M Goldfinger, Matthew S Harel, Michal Melloni, Lucia Schroeder, Charles E Deouell, Leon Y Mehta, Ashesh D Malach, Rafael Increasing suppression of saccade-related transients along the human visual hierarchy |
title | Increasing suppression of saccade-related transients along the human visual hierarchy |
title_full | Increasing suppression of saccade-related transients along the human visual hierarchy |
title_fullStr | Increasing suppression of saccade-related transients along the human visual hierarchy |
title_full_unstemmed | Increasing suppression of saccade-related transients along the human visual hierarchy |
title_short | Increasing suppression of saccade-related transients along the human visual hierarchy |
title_sort | increasing suppression of saccade-related transients along the human visual hierarchy |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576487/ https://www.ncbi.nlm.nih.gov/pubmed/28850030 http://dx.doi.org/10.7554/eLife.27819 |
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