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Cryo-EM structure of the SAGA and NuA4 coactivator subunit Tra1 at 3.7 angstrom resolution
Coactivator complexes SAGA and NuA4 stimulate transcription by post-translationally modifying chromatin. Both complexes contain the Tra1 subunit, a highly conserved 3744-residue protein from the Phosphoinositide 3-Kinase-related kinase (PIKK) family and a direct target for multiple sequence-specific...
Autores principales: | Díaz-Santín, Luis Miguel, Lukoyanova, Natasha, Aciyan, Emir, Cheung, Alan CM |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576489/ https://www.ncbi.nlm.nih.gov/pubmed/28767037 http://dx.doi.org/10.7554/eLife.28384 |
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