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Circular oligomerization is an intrinsic property of synaptotagmin
Previously, we showed that synaptotagmin1 (Syt1) forms Ca(2+)-sensitive ring-like oligomers on membranes containing acidic lipids and proposed a potential role in regulating neurotransmitter release (Zanetti et al., 2016). Here, we report that Syt1 assembles into similar ring-like oligomers in solut...
Autores principales: | Wang, Jing, Li, Feng, Bello, Oscar D, Sindelar, Charles Vaughn, Pincet, Frédéric, Krishnakumar, Shyam S, Rothman, James E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576491/ https://www.ncbi.nlm.nih.gov/pubmed/28850328 http://dx.doi.org/10.7554/eLife.27441 |
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