Transfer of in vitro-expanded naïve T cells after lymphodepletion enhances antitumor immunity through the induction of polyclonal antitumor effector T cells

The adoptive transfer of effector T cells combined with lymphodepletion has demonstrated promising antitumor effects in mice and humans, although the availability of tumor-specific T cells is limited. We and others have also demonstrated that the transfer of polyclonal naïve T cells induces tumor-sp...

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Detalles Bibliográficos
Autores principales: Tanaka, Tomohiro, Watanabe, Satoshi, Takahashi, Miho, Sato, Ko, Saida, Yu, Baba, Junko, Arita, Masashi, Sato, Miyuki, Ohtsubo, Aya, Shoji, Satoshi, Nozaki, Koichiro, Ichikawa, Kosuke, Kondo, Rie, Aoki, Nobumasa, Ohshima, Yasuyoshi, Sakagami, Takuro, Abe, Tetsuya, Moro, Hiroshi, Koya, Toshiyuki, Tanaka, Junta, Kagamu, Hiroshi, Yoshizawa, Hirohisa, Kikuchi, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576657/
https://www.ncbi.nlm.nih.gov/pubmed/28854279
http://dx.doi.org/10.1371/journal.pone.0183976

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