Tumor engraftment in patient-derived xenografts of pancreatic ductal adenocarcinoma is associated with adverse clinicopathological features and poor survival

Patient-derived xenograft (PDX) tumors are powerful tools to study cancer biology. However, the ability of PDX tumors to model the biological and histological diversity of pancreatic ductal adenocarcinoma (PDAC) is not well known. In this study, we subcutaneously implanted 133 primary and metastatic...

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Detalles Bibliográficos
Autores principales: Pergolini, Ilaria, Morales-Oyarvide, Vicente, Mino-Kenudson, Mari, Honselmann, Kim C., Rosenbaum, Matthew W., Nahar, Sabikun, Kem, Marina, Ferrone, Cristina R., Lillemoe, Keith D., Bardeesy, Nabeel, Ryan, David P., Thayer, Sarah P., Warshaw, Andrew L., Fernández-del Castillo, Carlos, Liss, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576681/
https://www.ncbi.nlm.nih.gov/pubmed/28854237
http://dx.doi.org/10.1371/journal.pone.0182855

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