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Efficient and accurate causal inference with hidden confounders from genome-transcriptome variation data

Mapping gene expression as a quantitative trait using whole genome-sequencing and transcriptome analysis allows to discover the functional consequences of genetic variation. We developed a novel method and ultra-fast software Findr for higly accurate causal inference between gene expression traits u...

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Detalles Bibliográficos
Autores principales: Wang, Lingfei, Michoel, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576763/
https://www.ncbi.nlm.nih.gov/pubmed/28821014
http://dx.doi.org/10.1371/journal.pcbi.1005703