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Efficient and accurate causal inference with hidden confounders from genome-transcriptome variation data
Mapping gene expression as a quantitative trait using whole genome-sequencing and transcriptome analysis allows to discover the functional consequences of genetic variation. We developed a novel method and ultra-fast software Findr for higly accurate causal inference between gene expression traits u...
Autores principales: | Wang, Lingfei, Michoel, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576763/ https://www.ncbi.nlm.nih.gov/pubmed/28821014 http://dx.doi.org/10.1371/journal.pcbi.1005703 |
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