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LET-99 functions in the astral furrowing pathway, where it is required for myosin enrichment in the contractile ring
The anaphase spindle determines the position of the cytokinesis furrow, such that the contractile ring assembles in an equatorial zone between the two spindle poles. Contractile ring formation is mediated by RhoA activation at the equator by the centralspindlin complex and midzone microtubules. Astr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576900/ https://www.ncbi.nlm.nih.gov/pubmed/28701343 http://dx.doi.org/10.1091/mbc.E16-12-0874 |