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TRIM9-dependent ubiquitination of DCC constrains kinase signaling, exocytosis, and axon branching

Extracellular netrin-1 and its receptor deleted in colorectal cancer (DCC) promote axon branching in developing cortical neurons. Netrin-dependent morphogenesis is preceded by multimerization of DCC, activation of FAK and Src family kinases, and increases in exocytic vesicle fusion, yet how these oc...

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Detalles Bibliográficos
Autores principales:	Plooster, Melissa, Menon, Shalini, Winkle, Cortney C., Urbina, Fabio L., Monkiewicz, Caroline, Phend, Kristen D., Weinberg, Richard J., Gupton, Stephanie L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576901/ https://www.ncbi.nlm.nih.gov/pubmed/28701345 http://dx.doi.org/10.1091/mbc.E16-08-0594

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