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ASCIZ/ATMIN is dispensable for ATM signaling in response to replication stress
The ATM kinase plays critical roles in the response to DNA double-strand breaks, and can also be activated by prolonged DNA replication blocks. It has recently been proposed that replication stress-dependent ATM activation is mediated by ASCIZ (also known as ATMIN, ZNF822), an essential developmenta...
Autores principales: | Liu, Rui, King, Ashleigh, Hoch, Nicolas C., Chang, Catherine, Kelly, Gemma L., Deans, Andrew J., Heierhorst, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576915/ https://www.ncbi.nlm.nih.gov/pubmed/28648892 http://dx.doi.org/10.1016/j.dnarep.2017.06.022 |
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