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Modeling of axonal endoplasmic reticulum network by spastic paraplegia proteins
Axons contain a smooth tubular endoplasmic reticulum (ER) network that is thought to be continuous with ER throughout the neuron; the mechanisms that form this axonal network are unknown. Mutations affecting reticulon or REEP proteins, with intramembrane hairpin domains that model ER membranes, caus...
Autores principales: | Yalçın, Belgin, Zhao, Lu, Stofanko, Martin, O'Sullivan, Niamh C, Kang, Zi Han, Roost, Annika, Thomas, Matthew R, Zaessinger, Sophie, Blard, Olivier, Patto, Alex L, Sohail, Anood, Baena, Valentina, Terasaki, Mark, O'Kane, Cahir J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576921/ https://www.ncbi.nlm.nih.gov/pubmed/28742022 http://dx.doi.org/10.7554/eLife.23882 |
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