A case report of EGFR mutant lung adenocarcinoma that acquired resistance to EGFR-tyrosine kinase inhibitors with T790M mutation and epithelial-to-mesenchymal transition

Although a secondary mutation and the epithelial-to-mesenchymal transition (EMT) are encountered very often in patients received the EGFR-TKI targeted treatment. The entire detrimental morphological change of the cancer entity was rare reported. Herein we report a case that acquired resistance to EG...

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Detalles Bibliográficos
Autores principales: Zhang, Nana, Wang, Depu, Li, Xiaofeng, Yang, Zhe, Zhang, Guanjun, Wang, Yili, Wang, Chunbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576958/
https://www.ncbi.nlm.nih.gov/pubmed/28879074
http://dx.doi.org/10.1016/j.rmcr.2017.08.015

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