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Review of redo-Kasai portoenterostomy for biliary atresia in the transition to the liver transplantation era

Portoenterostomy (PE) is the standard therapy for biliary atresia (BA). PE offers the chance of survival to children with BA. PE was the ultimate therapeutic modality for BA before liver transplantation (LT) was available. Failure of biliary drainage with PE was almost invariably fatal in children w...

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Detalles Bibliográficos
Autores principales: Sumida, Wataru, Uchida, Hiroo, Tanaka, Yujiro, Tainaka, Takahisa, Shirota, Chiyoe, Murase, Naruhiko, Oshima, Kazuo, Shirotsuki, Ryo, Chiba, Kousuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nagoya University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577027/
https://www.ncbi.nlm.nih.gov/pubmed/28878446
http://dx.doi.org/10.18999/nagjms.79.3.415
Descripción
Sumario:Portoenterostomy (PE) is the standard therapy for biliary atresia (BA). PE offers the chance of survival to children with BA. PE was the ultimate therapeutic modality for BA before liver transplantation (LT) was available. Failure of biliary drainage with PE was almost invariably fatal in children with BA. In such cases, redo-PE was performed to salvage patients following PE failure. PE remains the standard first treatment for BA despite the availability of LT. Further, redo-PE is also performed in a limited number of cases despite the development of LT as an alternative means of PE. However, there is concern that redo-PE increases morbidity at the time of subsequent LT. Laparoscopic redo-PE has recently been described. Laparoscopic redo-PE is expected to reduce complications of LT by preventing abdominal adhesion associated with repetitive surgery. In the present article, the future utility of redo-PE and the history of its changing roles are reviewed.