Elucidation of potential sites for antibody engineering by fluctuation editing

Target-specific monoclonal antibodies can be routinely acquired, but the sequences of naturally acquired antibodies are not always affinity-matured and methods that increase antigen affinity are desirable. Most biophysical studies have focused on the complementary determining region (CDR), which dir...

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Detalles Bibliográficos
Autores principales: Yanaka, Saeko, Moriwaki, Yoshitaka, Tsumoto, Kouhei, Sugase, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577056/
https://www.ncbi.nlm.nih.gov/pubmed/28855581
http://dx.doi.org/10.1038/s41598-017-10246-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577056/
https://www.ncbi.nlm.nih.gov/pubmed/28855581
http://dx.doi.org/10.1038/s41598-017-10246-9

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