Primary CD30-positive Diffuse Large B-cell Lymphoma in the Superior Vena Cava

Primary superior vena cava lymphoma originating from the endothelium of a large vein is very rare. A 70-year-old man was admitted to the hospital; computed tomography showed a tumor limited to the inside of the superior vena cava, completely occluding the vessel. A transjugular biopsy confirmed the...

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Detalles Bibliográficos
Autores principales: Nakamura, Shingen, Kagawa, Kumiko, Sumitani, Ryohei, Uemura, Munenori, Takahashi, Mamiko, Iwasa, Masami, Fujii, Shiro, Miki, Hirokazu, Abe, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577084/
https://www.ncbi.nlm.nih.gov/pubmed/28768978
http://dx.doi.org/10.2169/internalmedicine.56.8203
Descripción
Sumario:Primary superior vena cava lymphoma originating from the endothelium of a large vein is very rare. A 70-year-old man was admitted to the hospital; computed tomography showed a tumor limited to the inside of the superior vena cava, completely occluding the vessel. A transjugular biopsy confirmed the diagnosis of diffuse large B-cell lymphoma, which was diffusely positive for CD30. Rituximab monotherapy followed by five courses of R-CHOP chemotherapy induced a complete remission. There was no recurrence after two years. The pathophysiology of lymphoma derived from large vessels may be different from intravascular large B-cell lymphoma, which usually involves small vessels.

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