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Primary CD30-positive Diffuse Large B-cell Lymphoma in the Superior Vena Cava
Primary superior vena cava lymphoma originating from the endothelium of a large vein is very rare. A 70-year-old man was admitted to the hospital; computed tomography showed a tumor limited to the inside of the superior vena cava, completely occluding the vessel. A transjugular biopsy confirmed the...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577084/ https://www.ncbi.nlm.nih.gov/pubmed/28768978 http://dx.doi.org/10.2169/internalmedicine.56.8203 |
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author | Nakamura, Shingen Kagawa, Kumiko Sumitani, Ryohei Uemura, Munenori Takahashi, Mamiko Iwasa, Masami Fujii, Shiro Miki, Hirokazu Abe, Masahiro |
author_facet | Nakamura, Shingen Kagawa, Kumiko Sumitani, Ryohei Uemura, Munenori Takahashi, Mamiko Iwasa, Masami Fujii, Shiro Miki, Hirokazu Abe, Masahiro |
author_sort | Nakamura, Shingen |
collection | PubMed |
description | Primary superior vena cava lymphoma originating from the endothelium of a large vein is very rare. A 70-year-old man was admitted to the hospital; computed tomography showed a tumor limited to the inside of the superior vena cava, completely occluding the vessel. A transjugular biopsy confirmed the diagnosis of diffuse large B-cell lymphoma, which was diffusely positive for CD30. Rituximab monotherapy followed by five courses of R-CHOP chemotherapy induced a complete remission. There was no recurrence after two years. The pathophysiology of lymphoma derived from large vessels may be different from intravascular large B-cell lymphoma, which usually involves small vessels. |
format | Online Article Text |
id | pubmed-5577084 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-55770842017-09-01 Primary CD30-positive Diffuse Large B-cell Lymphoma in the Superior Vena Cava Nakamura, Shingen Kagawa, Kumiko Sumitani, Ryohei Uemura, Munenori Takahashi, Mamiko Iwasa, Masami Fujii, Shiro Miki, Hirokazu Abe, Masahiro Intern Med Case Report Primary superior vena cava lymphoma originating from the endothelium of a large vein is very rare. A 70-year-old man was admitted to the hospital; computed tomography showed a tumor limited to the inside of the superior vena cava, completely occluding the vessel. A transjugular biopsy confirmed the diagnosis of diffuse large B-cell lymphoma, which was diffusely positive for CD30. Rituximab monotherapy followed by five courses of R-CHOP chemotherapy induced a complete remission. There was no recurrence after two years. The pathophysiology of lymphoma derived from large vessels may be different from intravascular large B-cell lymphoma, which usually involves small vessels. The Japanese Society of Internal Medicine 2017-08-01 /pmc/articles/PMC5577084/ /pubmed/28768978 http://dx.doi.org/10.2169/internalmedicine.56.8203 Text en Copyright © 2017 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Nakamura, Shingen Kagawa, Kumiko Sumitani, Ryohei Uemura, Munenori Takahashi, Mamiko Iwasa, Masami Fujii, Shiro Miki, Hirokazu Abe, Masahiro Primary CD30-positive Diffuse Large B-cell Lymphoma in the Superior Vena Cava |
title | Primary CD30-positive Diffuse Large B-cell Lymphoma in the Superior Vena Cava |
title_full | Primary CD30-positive Diffuse Large B-cell Lymphoma in the Superior Vena Cava |
title_fullStr | Primary CD30-positive Diffuse Large B-cell Lymphoma in the Superior Vena Cava |
title_full_unstemmed | Primary CD30-positive Diffuse Large B-cell Lymphoma in the Superior Vena Cava |
title_short | Primary CD30-positive Diffuse Large B-cell Lymphoma in the Superior Vena Cava |
title_sort | primary cd30-positive diffuse large b-cell lymphoma in the superior vena cava |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577084/ https://www.ncbi.nlm.nih.gov/pubmed/28768978 http://dx.doi.org/10.2169/internalmedicine.56.8203 |
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