Biosynthesis of ilamycins featuring unusual building blocks and engineered production of enhanced anti-tuberculosis agents

Tuberculosis remains one of the world’s deadliest communicable diseases, novel anti-tuberculosis agents are urgently needed due to severe drug resistance and the co-epidemic of tuberculosis/human immunodeficiency virus. Here, we show the isolation of six anti-mycobacterial ilamycin congeners (1–6) b...

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Detalles Bibliográficos
Autores principales: Ma, Junying, Huang, Hongbo, Xie, Yunchang, Liu, Zhiyong, Zhao, Jin, Zhang, Chunyan, Jia, Yanxi, Zhang, Yun, Zhang, Hua, Zhang, Tianyu, Ju, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577134/
https://www.ncbi.nlm.nih.gov/pubmed/28855504
http://dx.doi.org/10.1038/s41467-017-00419-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577134/
https://www.ncbi.nlm.nih.gov/pubmed/28855504
http://dx.doi.org/10.1038/s41467-017-00419-5

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