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TCR–like antibodies mediate complement and antibody-dependent cellular cytotoxicity against Epstein-Barr virus–transformed B lymphoblastoid cells expressing different HLA-A*02 microvariants
Epstein-Barr virus (EBV) is a common gammaherpesvirus associated with various human malignancies. Antibodies with T cell receptor-like specificities (TCR-like mAbs) provide a means to target intracellular tumor- or virus-associated antigens by recognising their processed peptides presented on major...
Autores principales: | Lai, Junyun, Choo, Joanna Ai Ling, Tan, Wei Jian, Too, Chien Tei, Oo, Min Zin, Suter, Manuel A., Mustafa, Fatimah Bte, Srinivasan, Nalini, Chan, Conrad En Zuo, Lim, Andrew Guo Xian, Zhong, Youjia, Chan, Soh Ha, Hanson, Brendon J., Gascoigne, Nicholas R. J., MacAry, Paul A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577143/ https://www.ncbi.nlm.nih.gov/pubmed/28855662 http://dx.doi.org/10.1038/s41598-017-10265-6 |
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