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The Influence of Different Maternal Microbial Communities on the Development of Infant Gut and Oral Microbiota
Very few studies have analyzed how the composition of mother’s microbiota affects the development of infant’s gut and oral microbiota during the first months of life. Here, microbiota present in the mothers’ gut, vagina, breast milk, oral cavity, and mammary areola were compared with the gut and ora...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577157/ https://www.ncbi.nlm.nih.gov/pubmed/28855595 http://dx.doi.org/10.1038/s41598-017-09278-y |
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author | Drell, Tiina Štšepetova, Jelena Simm, Jaak Rull, Kristiina Aleksejeva, Aira Antson, Anne Tillmann, Vallo Metsis, Madis Sepp, Epp Salumets, Andres Mändar, Reet |
author_facet | Drell, Tiina Štšepetova, Jelena Simm, Jaak Rull, Kristiina Aleksejeva, Aira Antson, Anne Tillmann, Vallo Metsis, Madis Sepp, Epp Salumets, Andres Mändar, Reet |
author_sort | Drell, Tiina |
collection | PubMed |
description | Very few studies have analyzed how the composition of mother’s microbiota affects the development of infant’s gut and oral microbiota during the first months of life. Here, microbiota present in the mothers’ gut, vagina, breast milk, oral cavity, and mammary areola were compared with the gut and oral microbiota of their infants over the first six months following birth. Samples were collected from the aforementioned body sites from seven mothers and nine infants at three different time points over a 6-month period. Each sample was analyzed with 16S rRNA gene sequencing. The gut microbiota of the infants harbored distinct microbial communities that had low similarity with the various maternal microbiota communities. In contrast, the oral microbiota of the infants exhibited high similarity with the microbiota of the mothers’ breast milk, mammary areola and mouth. These results demonstrate that constant contact between microbial communities increases their similarity. A majority of the operational taxonomic units in infant gut and oral microbiota were also shared with the mothers’ gut and oral communities, respectively. The disparity between the similarity and the proportion of the OTUs shared between infants’ and mothers’ gut microbiota might be related to lower diversity and therefore competition in infants’ gut microbiota. |
format | Online Article Text |
id | pubmed-5577157 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-55771572017-09-01 The Influence of Different Maternal Microbial Communities on the Development of Infant Gut and Oral Microbiota Drell, Tiina Štšepetova, Jelena Simm, Jaak Rull, Kristiina Aleksejeva, Aira Antson, Anne Tillmann, Vallo Metsis, Madis Sepp, Epp Salumets, Andres Mändar, Reet Sci Rep Article Very few studies have analyzed how the composition of mother’s microbiota affects the development of infant’s gut and oral microbiota during the first months of life. Here, microbiota present in the mothers’ gut, vagina, breast milk, oral cavity, and mammary areola were compared with the gut and oral microbiota of their infants over the first six months following birth. Samples were collected from the aforementioned body sites from seven mothers and nine infants at three different time points over a 6-month period. Each sample was analyzed with 16S rRNA gene sequencing. The gut microbiota of the infants harbored distinct microbial communities that had low similarity with the various maternal microbiota communities. In contrast, the oral microbiota of the infants exhibited high similarity with the microbiota of the mothers’ breast milk, mammary areola and mouth. These results demonstrate that constant contact between microbial communities increases their similarity. A majority of the operational taxonomic units in infant gut and oral microbiota were also shared with the mothers’ gut and oral communities, respectively. The disparity between the similarity and the proportion of the OTUs shared between infants’ and mothers’ gut microbiota might be related to lower diversity and therefore competition in infants’ gut microbiota. Nature Publishing Group UK 2017-08-30 /pmc/articles/PMC5577157/ /pubmed/28855595 http://dx.doi.org/10.1038/s41598-017-09278-y Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Drell, Tiina Štšepetova, Jelena Simm, Jaak Rull, Kristiina Aleksejeva, Aira Antson, Anne Tillmann, Vallo Metsis, Madis Sepp, Epp Salumets, Andres Mändar, Reet The Influence of Different Maternal Microbial Communities on the Development of Infant Gut and Oral Microbiota |
title | The Influence of Different Maternal Microbial Communities on the Development of Infant Gut and Oral Microbiota |
title_full | The Influence of Different Maternal Microbial Communities on the Development of Infant Gut and Oral Microbiota |
title_fullStr | The Influence of Different Maternal Microbial Communities on the Development of Infant Gut and Oral Microbiota |
title_full_unstemmed | The Influence of Different Maternal Microbial Communities on the Development of Infant Gut and Oral Microbiota |
title_short | The Influence of Different Maternal Microbial Communities on the Development of Infant Gut and Oral Microbiota |
title_sort | influence of different maternal microbial communities on the development of infant gut and oral microbiota |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577157/ https://www.ncbi.nlm.nih.gov/pubmed/28855595 http://dx.doi.org/10.1038/s41598-017-09278-y |
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