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A signal-based method for finding driver modules of breast cancer metastasis to the lung

Tumor metastasis is mainly caused by somatic genomic alterations (SGAs) that perturb pathways regulating metastasis-relevant activities and thus help the primary tumor to adapt to the new microenvironment. Identifying drivers of metastasis, i.e. SGAs, sheds light on the metastasis mechanism and prov...

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Detalles Bibliográficos
Autores principales: Yan, Gaibo, Chen, Vicky, Lu, Xinghua, Lu, Songjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577160/
https://www.ncbi.nlm.nih.gov/pubmed/28855549
http://dx.doi.org/10.1038/s41598-017-09951-2

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