Highly efficient DNA-free gene disruption in the agricultural pest Ceratitis capitata by CRISPR-Cas9 ribonucleoprotein complexes

The Mediterranean fruitfly Ceratitis capitata (medfly) is an invasive agricultural pest of high economic impact and has become an emerging model for developing new genetic control strategies as an alternative to insecticides. Here, we report the successful adaptation of CRISPR-Cas9-based gene disrup...

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Detalles Bibliográficos
Autores principales: Meccariello, Angela, Monti, Simona Maria, Romanelli, Alessandra, Colonna, Rita, Primo, Pasquale, Inghilterra, Maria Grazia, Del Corsano, Giuseppe, Ramaglia, Antonio, Iazzetti, Giovanni, Chiarore, Antonia, Patti, Francesco, Heinze, Svenia D., Salvemini, Marco, Lindsay, Helen, Chiavacci, Elena, Burger, Alexa, Robinson, Mark D., Mosimann, Christian, Bopp, Daniel, Saccone, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577161/
https://www.ncbi.nlm.nih.gov/pubmed/28855635
http://dx.doi.org/10.1038/s41598-017-10347-5

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