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Hit-and-run programming of therapeutic cytoreagents using mRNA nanocarriers

Therapies based on immune cells have been applied for diseases ranging from cancer to diabetes. However, the viral and electroporation methods used to create cytoreagents are complex and expensive. Consequently, we develop targeted mRNA nanocarriers that are simply mixed with cells to reprogram them...

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Detalles Bibliográficos
Autores principales:	Moffett, H. F., Coon, M. E., Radtke, S., Stephan, S. B., McKnight, L., Lambert, A., Stoddard, B. L., Kiem, H. P., Stephan, M. T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577173/ https://www.ncbi.nlm.nih.gov/pubmed/28855514 http://dx.doi.org/10.1038/s41467-017-00505-8

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