Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis

Little is known regarding the epigenetic basis of atherosclerosis. Here we present the CD14+ blood monocyte transcriptome and epigenome signatures associated with human atherosclerosis. The transcriptome signature includes transcription coactivator, ARID5B, which is known to form a chromatin derepre...

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Detalles Bibliográficos
Autores principales: Liu, Yongmei, Reynolds, Lindsay M., Ding, Jingzhong, Hou, Li, Lohman, Kurt, Young, Tracey, Cui, Wei, Huang, Zhiqing, Grenier, Carole, Wan, Ma, Stunnenberg, Hendrik G., Siscovick, David, Hou, Lifang, Psaty, Bruce M., Rich, Stephen S., Rotter, Jerome I., Kaufman, Joel D., Burke, Gregory L., Murphy, Susan, Jacobs, David R., Post, Wendy, Hoeschele, Ina, Bell, Douglas A., Herrington, David, Parks, John S., Tracy, Russell P., McCall, Charles E., Stein, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577184/
https://www.ncbi.nlm.nih.gov/pubmed/28855511
http://dx.doi.org/10.1038/s41467-017-00517-4

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