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Increased cross-modal functional connectivity in cochlear implant users
Previous studies have reported increased cross-modal auditory and visual cortical activation in cochlear implant (CI) users, suggesting cross-modal reorganization of both visual and auditory cortices in CI users as a consequence of sensory deprivation and restoration. How these processes affect the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577186/ https://www.ncbi.nlm.nih.gov/pubmed/28855675 http://dx.doi.org/10.1038/s41598-017-10792-2 |
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author | Chen, Ling-Chia Puschmann, Sebastian Debener, Stefan |
author_facet | Chen, Ling-Chia Puschmann, Sebastian Debener, Stefan |
author_sort | Chen, Ling-Chia |
collection | PubMed |
description | Previous studies have reported increased cross-modal auditory and visual cortical activation in cochlear implant (CI) users, suggesting cross-modal reorganization of both visual and auditory cortices in CI users as a consequence of sensory deprivation and restoration. How these processes affect the functional connectivity of the auditory and visual system in CI users is however unknown. We here investigated task-induced intra-modal functional connectivity between hemispheres for both visual and auditory cortices and cross-modal functional connectivity between visual and auditory cortices using functional near infrared spectroscopy in post-lingually deaf CI users and age-matched normal hearing controls. Compared to controls, CI users exhibited decreased intra-modal functional connectivity between hemispheres and increased cross-modal functional connectivity between visual and left auditory cortices for both visual and auditory stimulus processing. Importantly, the difference between cross-modal functional connectivity for visual and for auditory stimuli correlated with speech recognition outcome in CI users. Higher cross-modal connectivity for auditory than for visual stimuli was associated with better speech recognition abilities, pointing to a new pattern of functional reorganization that is related to successful hearing restoration with a CI. |
format | Online Article Text |
id | pubmed-5577186 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-55771862017-09-01 Increased cross-modal functional connectivity in cochlear implant users Chen, Ling-Chia Puschmann, Sebastian Debener, Stefan Sci Rep Article Previous studies have reported increased cross-modal auditory and visual cortical activation in cochlear implant (CI) users, suggesting cross-modal reorganization of both visual and auditory cortices in CI users as a consequence of sensory deprivation and restoration. How these processes affect the functional connectivity of the auditory and visual system in CI users is however unknown. We here investigated task-induced intra-modal functional connectivity between hemispheres for both visual and auditory cortices and cross-modal functional connectivity between visual and auditory cortices using functional near infrared spectroscopy in post-lingually deaf CI users and age-matched normal hearing controls. Compared to controls, CI users exhibited decreased intra-modal functional connectivity between hemispheres and increased cross-modal functional connectivity between visual and left auditory cortices for both visual and auditory stimulus processing. Importantly, the difference between cross-modal functional connectivity for visual and for auditory stimuli correlated with speech recognition outcome in CI users. Higher cross-modal connectivity for auditory than for visual stimuli was associated with better speech recognition abilities, pointing to a new pattern of functional reorganization that is related to successful hearing restoration with a CI. Nature Publishing Group UK 2017-08-30 /pmc/articles/PMC5577186/ /pubmed/28855675 http://dx.doi.org/10.1038/s41598-017-10792-2 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Chen, Ling-Chia Puschmann, Sebastian Debener, Stefan Increased cross-modal functional connectivity in cochlear implant users |
title | Increased cross-modal functional connectivity in cochlear implant users |
title_full | Increased cross-modal functional connectivity in cochlear implant users |
title_fullStr | Increased cross-modal functional connectivity in cochlear implant users |
title_full_unstemmed | Increased cross-modal functional connectivity in cochlear implant users |
title_short | Increased cross-modal functional connectivity in cochlear implant users |
title_sort | increased cross-modal functional connectivity in cochlear implant users |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577186/ https://www.ncbi.nlm.nih.gov/pubmed/28855675 http://dx.doi.org/10.1038/s41598-017-10792-2 |
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