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Genetic studies in mice directly link oocytes produced during adulthood to ovarian function and natural fertility

Multiple labs have reported that mammalian ovaries contain oogonial stem cells (OSCs), which can differentiate into oocytes that fertilize to produce offspring. However, the physiological relevance of these observations to adult ovarian function is unknown. Here we performed targeted and reversible...

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Detalles Bibliográficos
Autores principales: Wang, Ning, Satirapod, Chonthicha, Ohguchi, Yasuyo, Park, Eun-Sil, Woods, Dori C., Tilly, Jonathan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577229/
https://www.ncbi.nlm.nih.gov/pubmed/28855574
http://dx.doi.org/10.1038/s41598-017-10033-6