Activation of NADPH oxidases leads to DNA damage in esophageal cells

Gastroesophageal reflux disease (GERD) is the strongest known risk factor for esophageal adenocarcinoma. In the center of tumorigenic events caused by GERD is repeated damage of esophageal tissues by the refluxate. In this study, we focused on a genotoxic aspect of exposure of esophageal cells to ac...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Vikas, Gokulan, Ravindran Caspa, Horvat, Andela, Yermalitskaya, Liudmila, Korolkova, Olga, Washington, Kay M., El-Rifai, Wael, Dikalov, Sergey I., Zaika, Alexander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577233/
https://www.ncbi.nlm.nih.gov/pubmed/28855537
http://dx.doi.org/10.1038/s41598-017-09620-4

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