Cargando…
MHC matching improves engraftment of iPSC-derived neurons in non-human primates
The banking of human leukocyte antigen (HLA)-homozygous-induced pluripotent stem cells (iPSCs) is considered a future clinical strategy for HLA-matched cell transplantation to reduce immunological graft rejection. Here we show the efficacy of major histocompatibility complex (MHC)-matched allogeneic...
Autores principales: | Morizane, Asuka, Kikuchi, Tetsuhiro, Hayashi, Takuya, Mizuma, Hiroshi, Takara, Sayuki, Doi, Hisashi, Mawatari, Aya, Glasser, Matthew F., Shiina, Takashi, Ishigaki, Hirohito, Itoh, Yasushi, Okita, Keisuke, Yamasaki, Emi, Doi, Daisuke, Onoe, Hirotaka, Ogasawara, Kazumasa, Yamanaka, Shinya, Takahashi, Jun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577234/ https://www.ncbi.nlm.nih.gov/pubmed/28855509 http://dx.doi.org/10.1038/s41467-017-00926-5 |
Ejemplares similares
-
Direct Comparison of Autologous and Allogeneic Transplantation of iPSC-Derived Neural Cells in the Brain of a Nonhuman Primate
por: Morizane, Asuka, et al.
Publicado: (2013) -
MHC-identical and transgenic cynomolgus macaques for preclinical studies
por: Ishigaki, Hirohito, et al.
Publicado: (2018) -
Successful Transplantation of Retinal Pigment Epithelial Cells from MHC Homozygote iPSCs in MHC-Matched Models
por: Sugita, Sunao, et al.
Publicado: (2016) -
Competency of iPSC-derived retinas in MHC-mismatched transplantation in non-human primates
por: Uyama, Hirofumi, et al.
Publicado: (2022) -
Detection of Retinal Pigment Epithelium-Specific Antibody in iPSC-Derived Retinal Pigment Epithelium Transplantation Models
por: Sugita, Sunao, et al.
Publicado: (2017)