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Retinol saturase coordinates liver metabolism by regulating ChREBP activity

The liver integrates multiple metabolic pathways to warrant systemic energy homeostasis. An excessive lipogenic flux due to chronic dietary stimulation contributes to the development of hepatic steatosis, dyslipidemia and hyperglycemia. Here we show that the oxidoreductase retinol saturase (RetSat)...

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Detalles Bibliográficos
Autores principales:	Heidenreich, Steffi, Witte, Nicole, Weber, Pamela, Goehring, Isabel, Tolkachov, Alexander, von Loeffelholz, Christian, Döcke, Stephanie, Bauer, Michael, Stockmann, Martin, Pfeiffer, Andreas F. H., Birkenfeld, Andreas L., Pietzke, Matthias, Kempa, Stefan, Muenzner, Matthias, Schupp, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577314/ https://www.ncbi.nlm.nih.gov/pubmed/28855500 http://dx.doi.org/10.1038/s41467-017-00430-w

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