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RNAi combining Sleeping Beauty transposon system inhibits ex vivo expression of foot-and-mouth disease virus VP1 in transgenic sheep cells

Foot and mouth disease, which is induced by the foot and mouth disease virus (FMDV), takes its toll on the cloven-hoofed domestic animals. The VP1 gene in FMDV genome encodes the viral capsid, a vital element for FMDV replication. Sleeping Beauty (SB) is an active DNA-transposon system responsible f...

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Detalles Bibliográficos
Autores principales:	Deng, Shoulong, Li, Guangdong, Yu, Kun, Tian, Xiuzhi, Wang, Feng, Li, Wenting, Jiang, Wuqi, Ji, Pengyun, Han, Hongbing, Fu, Juncai, Zhang, Xiaosheng, Zhang, Jinlong, Liu, Yixun, Lian, Zhengxing, Liu, Guoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577316/ https://www.ncbi.nlm.nih.gov/pubmed/28855524 http://dx.doi.org/10.1038/s41598-017-09302-1

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