Cargando…

The Chromatin Structure Differentially Impacts High-Specificity CRISPR-Cas9 Nuclease Strategies

Detalles Bibliográficos
Autores principales:	Chen, Xiaoyu, Liu, Jin, Janssen, Josephine M., Gonçalves, Manuel A.F.V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2017
Materias:	Letter to the Editor
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577405/ https://www.ncbi.nlm.nih.gov/pubmed/28918055 http://dx.doi.org/10.1016/j.omtn.2017.08.005

Ejemplares similares

The Chromatin Structure of CRISPR-Cas9 Target DNA Controls the Balance between Mutagenic and Homology-Directed Gene-Editing Events
por: Janssen, Josephine M., et al.
Publicado: (2019)

Adenoviral vector delivery of RNA-guided CRISPR/Cas9 nuclease complexes induces targeted mutagenesis in a diverse array of human cells
por: Maggio, Ignazio, et al.
Publicado: (2014)

Engineered CRISPR-Cas9 nucleases with altered PAM specificities
por: Kleinstiver, Benjamin P., et al.
Publicado: (2015)

High-capacity adenovector delivery of forced CRISPR-Cas9 heterodimers fosters precise chromosomal deletions in human cells
por: Tasca, Francesca, et al.
Publicado: (2023)

Applications of Alternative Nucleases in the Age of CRISPR/Cas9
por: Guha, Tuhin K., et al.
Publicado: (2017)

Activities and specificities of CRISPR/Cas9 and Cas12a nucleases for targeted mutagenesis in maize
por: Lee, Keunsub, et al.
Publicado: (2018)

Painting a specific chromosome with CRISPR/Cas9 for live-cell imaging
por: Zhou, Yuexin, et al.
Publicado: (2017)

Application of CRISPR/Cas9 Nuclease in Amphioxus Genome Editing
por: Su, Liuru, et al.
Publicado: (2020)

Targeted gene editing by transfection of in vitro reconstituted Streptococcus thermophilus Cas9 nuclease complex
por: Glemzaite, Monika, et al.
Publicado: (2015)

Probing the impact of chromatin conformation on genome editing tools
por: Chen, Xiaoyu, et al.
Publicado: (2016)

Large-scale genome editing based on high-capacity adenovectors and CRISPR-Cas9 nucleases rescues full-length dystrophin synthesis in DMD muscle cells
por: Tasca, Francesca, et al.
Publicado: (2022)

Selection-free gene repair after adenoviral vector transduction of designer nucleases: rescue of dystrophin synthesis in DMD muscle cell populations
por: Maggio, Ignazio, et al.
Publicado: (2016)

Target-dependent nickase activities of CRISPR-Cas nucleases Cpf1 and Cas9
por: Hua Fu, Becky Xu, et al.
Publicado: (2019)

Genome Engineering of Drosophila with the CRISPR RNA-Guided Cas9 Nuclease
por: Gratz, Scott J., et al.
Publicado: (2013)

CRISPR clear? Dimeric Cas9-Fok1 nucleases improve genome-editing specificity
por: Zhang, Hongmei, et al.
Publicado: (2014)

Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq
por: Kim, Daesik, et al.
Publicado: (2016)

Recent Advances in Improving Gene-Editing Specificity through CRISPR–Cas9 Nuclease Engineering
por: Huang, Xiaoqiang, et al.
Publicado: (2022)

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
por: Fu, Yanfang, et al.
Publicado: (2014)

Development of sequence-specific antimicrobials based on programmable CRISPR-Cas nucleases
por: Bikard, David, et al.
Publicado: (2014)

Engineering of Primary Human B cells with CRISPR/Cas9 Targeted Nuclease
por: Johnson, Matthew J., et al.
Publicado: (2018)

Altered DNA repair pathway engagement by engineered CRISPR-Cas9 nucleases
por: Chauhan, Vikash P., et al.
Publicado: (2023)

Targeted gene disruption in Xenopus laevis using CRISPR/Cas9
por: Wang, Fengqin, et al.
Publicado: (2015)

Adenoviral vectors encoding CRISPR/Cas9 multiplexes rescue dystrophin synthesis in unselected populations of DMD muscle cells
por: Maggio, Ignazio, et al.
Publicado: (2016)

Editor's cut: DNA cleavage by CRISPR RNA-guided nucleases Cas9 and Cas12a
por: Swartjes, Thomas, et al.
Publicado: (2020)

CRISPR/Cas9-mediated precise targeted mutagenesis of phytoene desaturase in celery
por: Liu, Jie-Xia, et al.
Publicado: (2022)

Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells
por: Kleinstiver, Benjamin P., et al.
Publicado: (2016)

Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9
por: Koo, Taeyoung, et al.
Publicado: (2015)

Efficient CRISPR/Cas9-Mediated Genome Editing in Mice by Zygote Electroporation of Nuclease
por: Qin, Wenning, et al.
Publicado: (2015)

Prevalence of Pre-existing Antibodies to CRISPR-Associated Nuclease Cas9 in the USA Population
por: Simhadri, Vijaya L., et al.
Publicado: (2018)

A CRISPR/CAS9‐based strategy targets the personalized chimeric neosequence in fusion‐driven cancer genome for precision medicine
por: Huang, Wei, et al.
Publicado: (2021)

Seamless site-directed mutagenesis of the Saccharomyces cerevisiae genome using CRISPR-Cas9
por: Biot-Pelletier, Damien, et al.
Publicado: (2016)

CRISPR/Cas9-mediated PINK1 deletion leads to neurodegeneration in rhesus monkeys
por: Yang, Weili, et al.
Publicado: (2019)

Unintended on-target chromosomal instability following CRISPR/Cas9 single gene targeting
por: Przewrocka, J., et al.
Publicado: (2020)

Structural basis for the activation of a compact CRISPR-Cas13 nuclease
por: Deng, Xiangyu, et al.
Publicado: (2023)

Casilio: a versatile CRISPR-Cas9-Pumilio hybrid for gene regulation and genomic labeling
por: Cheng, Albert W, et al.
Publicado: (2016)

Genome-scale CRISPR-Cas9 knockout screening in gastrointestinal stromal tumor with Imatinib resistance
por: Cao, Jie, et al.
Publicado: (2018)

CRISPR/Cas9 from bench to bedside: what clinicians need to know before application?
por: Li, Zi-Qing, et al.
Publicado: (2020)

CRISPR/Cas9‐based functional analysis of yellow gene in the diamondback moth, Plutella xylostella
por: Wang, Yajun, et al.
Publicado: (2020)

Elimination of an unfavorable allele conferring pod shattering in an elite soybean cultivar by CRISPR/Cas9
por: Zhang, Zhihui, et al.
Publicado: (2022)

A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses
por: Wang, Jiuyu, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_dn3610tv449am7mp02n9a2eidv