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Alveolar socket preservation with demineralised bovine bone mineral and a collagen matrix

PURPOSE: The aim of the present study was to evaluate the healing of post-extraction sockets following alveolar ridge preservation clinically, radiologically, and histologically. METHODS: Overall, 7 extraction sockets in 7 patients were grafted with demineralised bovine bone mineral and covered with...

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Autores principales: Maiorana, Carlo, Poli, Pier Paolo, Deflorian, Matteo, Testori, Tiziano, Mandelli, Federico, Nagursky, Heiner, Vinci, Raffaele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Academy of Periodontology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577438/
https://www.ncbi.nlm.nih.gov/pubmed/28861284
http://dx.doi.org/10.5051/jpis.2017.47.4.194
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author Maiorana, Carlo
Poli, Pier Paolo
Deflorian, Matteo
Testori, Tiziano
Mandelli, Federico
Nagursky, Heiner
Vinci, Raffaele
author_facet Maiorana, Carlo
Poli, Pier Paolo
Deflorian, Matteo
Testori, Tiziano
Mandelli, Federico
Nagursky, Heiner
Vinci, Raffaele
author_sort Maiorana, Carlo
collection PubMed
description PURPOSE: The aim of the present study was to evaluate the healing of post-extraction sockets following alveolar ridge preservation clinically, radiologically, and histologically. METHODS: Overall, 7 extraction sockets in 7 patients were grafted with demineralised bovine bone mineral and covered with a porcine-derived non-crosslinked collagen matrix (CM). Soft tissue healing was clinically evaluated on the basis of a specific healing index. Horizontal and vertical ridge dimensional changes were assessed clinically and radiographically at baseline and 6 months after implant placement. For histological and histomorphometric analysis, bone biopsies were harvested from the augmented sites during implant surgery 6 months after the socket preservation procedure. RESULTS: Clinically, healing proceeded uneventfully in all the sockets. A trend towards reduced horizontal and vertical socket dimensions was observed from baseline to the final examination. The mean width and height of resorption were 1.21 mm (P=0.005) and 0.46 mm (P=0.004), respectively. Histologically, residual xenograft particles (31.97%±3.52%) were surrounded by either newly formed bone (16.02%±7.06%) or connective tissue (50.67%±8.42%) without fibrous encapsulation. The CM underwent a physiological substitution process in favour of well-vascularised collagen-rich connective tissue. CONCLUSIONS: Socket preservation using demineralised bovine bone mineral in combination with CM provided stable dimensional changes of the alveolar ridge associated with good re-epithelialisation of the soft tissues during a 6-month healing period.
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spelling pubmed-55774382017-08-31 Alveolar socket preservation with demineralised bovine bone mineral and a collagen matrix Maiorana, Carlo Poli, Pier Paolo Deflorian, Matteo Testori, Tiziano Mandelli, Federico Nagursky, Heiner Vinci, Raffaele J Periodontal Implant Sci Research Article PURPOSE: The aim of the present study was to evaluate the healing of post-extraction sockets following alveolar ridge preservation clinically, radiologically, and histologically. METHODS: Overall, 7 extraction sockets in 7 patients were grafted with demineralised bovine bone mineral and covered with a porcine-derived non-crosslinked collagen matrix (CM). Soft tissue healing was clinically evaluated on the basis of a specific healing index. Horizontal and vertical ridge dimensional changes were assessed clinically and radiographically at baseline and 6 months after implant placement. For histological and histomorphometric analysis, bone biopsies were harvested from the augmented sites during implant surgery 6 months after the socket preservation procedure. RESULTS: Clinically, healing proceeded uneventfully in all the sockets. A trend towards reduced horizontal and vertical socket dimensions was observed from baseline to the final examination. The mean width and height of resorption were 1.21 mm (P=0.005) and 0.46 mm (P=0.004), respectively. Histologically, residual xenograft particles (31.97%±3.52%) were surrounded by either newly formed bone (16.02%±7.06%) or connective tissue (50.67%±8.42%) without fibrous encapsulation. The CM underwent a physiological substitution process in favour of well-vascularised collagen-rich connective tissue. CONCLUSIONS: Socket preservation using demineralised bovine bone mineral in combination with CM provided stable dimensional changes of the alveolar ridge associated with good re-epithelialisation of the soft tissues during a 6-month healing period. Korean Academy of Periodontology 2017-08 2017-08-11 /pmc/articles/PMC5577438/ /pubmed/28861284 http://dx.doi.org/10.5051/jpis.2017.47.4.194 Text en Copyright © 2017. Korean Academy of Periodontology https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/).
spellingShingle Research Article
Maiorana, Carlo
Poli, Pier Paolo
Deflorian, Matteo
Testori, Tiziano
Mandelli, Federico
Nagursky, Heiner
Vinci, Raffaele
Alveolar socket preservation with demineralised bovine bone mineral and a collagen matrix
title Alveolar socket preservation with demineralised bovine bone mineral and a collagen matrix
title_full Alveolar socket preservation with demineralised bovine bone mineral and a collagen matrix
title_fullStr Alveolar socket preservation with demineralised bovine bone mineral and a collagen matrix
title_full_unstemmed Alveolar socket preservation with demineralised bovine bone mineral and a collagen matrix
title_short Alveolar socket preservation with demineralised bovine bone mineral and a collagen matrix
title_sort alveolar socket preservation with demineralised bovine bone mineral and a collagen matrix
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577438/
https://www.ncbi.nlm.nih.gov/pubmed/28861284
http://dx.doi.org/10.5051/jpis.2017.47.4.194
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