An in vivo genetic screen in Drosophila identifies the orthologue of human cancer/testis gene SPO11 among a network of targets to inhibit lethal(3)malignant brain tumour growth

Using transgenic RNAi technology, we have screened over 4000 genes to identify targets to inhibit malignant growth caused by the loss of function of lethal(3)malignant brain tumour in Drosophila in vivo. We have identified 131 targets, which belong to a wide range of gene ontologies. Most of these t...

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Detalles Bibliográficos
Autores principales: Rossi, Fabrizio, Molnar, Cristina, Hashiyama, Kazuya, Heinen, Jan P., Pampalona, Judit, Llamazares, Salud, Reina, José, Hashiyama, Tomomi, Rai, Madhulika, Pollarolo, Giulia, Fernández-Hernández, Ismael, Gonzalez, Cayetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577452/
https://www.ncbi.nlm.nih.gov/pubmed/28855394
http://dx.doi.org/10.1098/rsob.170156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577452/
https://www.ncbi.nlm.nih.gov/pubmed/28855394
http://dx.doi.org/10.1098/rsob.170156

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