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SUMO, a small, but powerful, regulator of double-strand break repair

The response to a DNA double-stranded break in mammalian cells is a process of sensing and signalling the lesion. It results in halting the cell cycle and local transcription and in the mediation of the DNA repair process itself. The response is launched through a series of post-translational modifi...

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Detalles Bibliográficos
Autores principales: Garvin, Alexander J., Morris, Joanna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577459/
https://www.ncbi.nlm.nih.gov/pubmed/28847818
http://dx.doi.org/10.1098/rstb.2016.0281