The helicase, DDX3X, interacts with poly(A)-binding protein 1 (PABP1) and caprin-1 at the leading edge of migrating fibroblasts and is required for efficient cell spreading

DDX3X, a helicase, can interact directly with mRNA and translation initiation factors, regulating the selective translation of mRNAs that contain a structured 5′ untranslated region. This activity modulates the expression of mRNAs controlling cell cycle progression and mRNAs regulating actin dynamic...

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Detalles Bibliográficos
Autores principales: Copsey, Alice C., Cooper, Simon, Parker, Robert, Lineham, Ella, Lapworth, Cuzack, Jallad, Deema, Sweet, Steve, Morley, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577505/
https://www.ncbi.nlm.nih.gov/pubmed/28733330
http://dx.doi.org/10.1042/BCJ20170354

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