Cargando…

Sensitive Detection of α-Conotoxin GI in Human Plasma Using a Solid-Phase Extraction Column and LC-MS/MS

α-conotoxin GI, a short peptide toxin in the venom of Conus geographus, is composed of 13 amino acids and two disulfide bonds. It is the most toxic component of Conus geographus venom with estimated lethal doses of 0.029–0.038 mg/kg for humans. There is currently no reported analytical method for th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Shuo, Yang, Bo, Yan, Liangping, Dai, Qiuyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577569/ https://www.ncbi.nlm.nih.gov/pubmed/28788055 http://dx.doi.org/10.3390/toxins9080235

Ejemplares similares

Analysis of Serotonin in Human Feces Using Solid Phase Extraction and Column-Switching LC-MS/MS
por: Hirabayashi, Yukiko, et al.
Publicado: (2020)

Optimizing oxytocin LC-MS/MS sensitivity by choosing the right column
por: Ackermans, Mariëtte T.
Publicado: (2021)

LC-MS/MS Quantification of Tramadol and Gabapentin Utilizing Solid Phase Extraction
por: Nagaraju, Pappula, et al.
Publicado: (2018)

Development and validation of an automated solid-phase extraction-LC-MS/MS method for the bioanalysis of fluoxetine in human plasma
por: Ahmad, Ishtiaque, et al.
Publicado: (2021)

Optimisation of Solid-Phase Extraction and LC-MS/MS Analysis of Six Breast Cancer Drugs in Patient Plasma Samples
por: Turković, Lu, et al.
Publicado: (2023)

Sensitive Detection of 8-Nitroguanine in DNA by Chemical Derivatization Coupled with Online Solid-Phase Extraction LC-MS/MS
por: Hu, Chiung-Wen, et al.
Publicado: (2018)

The 3/4- and 3/6-Subfamily Variants of α-Conotoxins GI and MI Exhibit Potent Inhibitory Activity against Muscular Nicotinic Acetylcholine Receptors
por: Ma, Xiaoli, et al.
Publicado: (2021)

An LC–MS/MS method for the determination of budesonide and 16α-hydroxyprednisolone in dog plasma
por: Gazzotti, Teresa, et al.
Publicado: (2016)

Dispersive Solid–Liquid Extraction Coupled with LC-MS/MS for the Determination of Sulfonylurea Herbicides in Strawberries
por: Song, Nho-Eul, et al.
Publicado: (2019)

Systematic Assessment of Seven Solvent and Solid-Phase Extraction Methods for Metabolomics Analysis of Human Plasma by LC-MS
por: Sitnikov, Dmitri G., et al.
Publicado: (2016)

Sensitive determination of gentamicin in plasma using ion-exchange solid-phase extraction followed by UHPLC-MS/MS analysis
por: Anibaletto dos Santos, Ana Laura, et al.
Publicado: (2021)

Fast and sensitive LC–MS/MS method for the simultaneous determination of lisinopril and hydrochlorothiazide in human plasma
por: Shah, Jaivik V., et al.
Publicado: (2017)

Optimization of a Multiresidue Analysis of 65 Pesticides in Surface Water Using Solid-Phase Extraction by LC-MS/MS
por: Nakhjavan, Bahar, et al.
Publicado: (2021)

Development and validation of Lenalidomide in human plasma by LC-MS/MS
por: Ranganathan, Premanand, et al.
Publicado: (2019)

Determination of Organophosphorus Esters in Fall Protection Equipment by Accelerated Solvent Extraction and Solid-Phase Extraction Coupled with LC-MS/MS Detection
por: Li, Haihong, et al.
Publicado: (2021)

Comparison of Two Solid-Phase Extraction (SPE) Methods for the Identification and Quantification of Porcine Retinal Protein Markers by LC-MS/MS
por: Schmelter, Carsten, et al.
Publicado: (2018)

Rapid and Sensitive Determination of Timosaponin AIII in Rat Plasma by LC-MS/MS and Its Pharmacokinetic Application
por: Liu, Yanping, et al.
Publicado: (2013)

Determination of Scopolamine Distribution in Plasma and Brain by LC-MS/MS in Rats
por: Chen, Juan, et al.
Publicado: (2022)

Quantification of 3,4-Dimethyl-1H-Pyrazole Using Ion-Pair LC–MS/MS on a Reversed-Phase Column
por: Doran, Gregory S, et al.
Publicado: (2022)

Determination of Phthalate Metabolites in Human Serum and Urine as Biomarkers for Phthalate Exposure Using Column-Switching LC-MS/MS
por: Jeong, Jee Yeon, et al.
Publicado: (2011)

LC, MS(n) and LC–MS/MS studies for the characterization of degradation products of amlodipine
por: Tiwari, Ravi N., et al.
Publicado: (2015)

Development, Validation, and Comparison of Two Mass Spectrometry Methods (LC-MS/HRMS and LC-MS/MS) for the Quantification of Rituximab in Human Plasma
por: Millet, Aurélien, et al.
Publicado: (2021)

Sensitive and rapid determination of amantadine without derivatization in human plasma by LC–MS/MS for a bioequivalence study
por: Bhadoriya, Abhaysingh, et al.
Publicado: (2018)

Development and validation of a simple, selective, and sensitive LC-MS/MS assay for the quantification of remdesivir in human plasma
por: Nguyen, Ryan, et al.
Publicado: (2021)

Sensitive LC-MS/MS Method for the Quantification of Macrocyclic Gα(q) Protein Inhibitors in Biological Samples
por: Kuschak, Markus, et al.
Publicado: (2020)

An LC-MS Assay with Isocratic Separation and On-line Solid Phase Extraction to Improve the Routine Therapeutic Drug Monitoring of Busulfan in Plasma
por: Ialongo, Cristiano, et al.
Publicado: (2017)

Bioequivalance and pharmacokinetic study of febuxostat in human plasma by using LC-MS/MS with liquid liquid extraction method
por: Chandu, Babu Rao, et al.
Publicado: (2013)

Quantification of cGMP in human plasma by isotope dilution LC-MS/MS
por: Martens-Lobenhoffer, Jens, et al.
Publicado: (2009)

Analytical Challenges: Determination of Tetrodotoxin in Human Urine and Plasma by LC-MS/MS
por: Leung, Kelvin Sze-Yin, et al.
Publicado: (2011)

Fast and Simple LC-MS/MS Method for Rifampicin Quantification in Human Plasma
por: Temova Rakuša, Žane, et al.
Publicado: (2019)

Determination and pharmacokinetics study of UK-5099 in mouse plasma by LC–MS/MS
por: Zeng, Qingyuan, et al.
Publicado: (2022)

Bioavailable Sulforaphane Quantitation in Plasma by LC–MS/MS Is Enhanced by Blocking Thiols
por: Grady, Rachel S., et al.
Publicado: (2023)

In Vivo Metabolism Study of Xiamenmycin A in Mouse Plasma by UPLC-QTOF-MS and LC-MS/MS
por: Lei, Feng, et al.
Publicado: (2015)

Deep and Highly Sensitive Proteome Coverage by LC-MS/MS Without Prefractionation
por: Thakur, Suman S., et al.
Publicado: (2011)

A Sensitive LC-MS/MS Method for Palytoxin Using Lithium Cationization
por: Klijnstra, Mirjam D., et al.
Publicado: (2018)

LC-MS/MS for Ultra-Sensitive Quantification of Multiple Estrogens in the Blood and Brain
por: Jalabert, Cecilia, et al.
Publicado: (2021)

Enhanced LC-ESI-MS/MS Sensitivity by Cationic Derivatization of Organophosphorus Acids
por: Shamai Yamin, Tamar, et al.
Publicado: (2023)

Quantitation of cyclic dinucleotides by reversed-phase LC-MS/MS
por: Spangler, Christian, et al.
Publicado: (2009)

Fecal metabolite analysis of Japanese macaques in Yakushima by LC-MS/MS and LC-QTOF-MS
por: TSUCHIDA, Sayaka, et al.
Publicado: (2021)

Phase separation liquid-liquid extraction for the quantification of 8-iso-Prostaglandin F2 Alpha in human plasma by LC-MS/MS
por: Tomov, Desislav G., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_cobkhpu4v0krs4ck4b56v0f8dc