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Comprehensive genomic profiling in routine clinical practice leads to a low rate of benefit from genotype-directed therapy
BACKGROUND: Describe a single-center real-world experience with comprehensive genomic profiling (CGP) to identify genotype directed therapy (GDT) options for patients with malignancies refractory to standard treatment options. METHODS: Patients who had CGP by a CLIA-certified laboratory between Nove...
Autores principales: | Hilal, Talal, Nakazawa, Mary, Hodskins, Jacob, Villano, John L., Mathew, Aju, Goel, Guarav, Wagner, Lars, Arnold, Susanne M., DeSimone, Philip, Anthony, Lowell B., Hosein, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577820/ https://www.ncbi.nlm.nih.gov/pubmed/28854908 http://dx.doi.org/10.1186/s12885-017-3587-8 |
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