Comparative In Vitro Controlled Release Studies on the Chronobiotic Hormone Melatonin from Cyclodextrins-Containing Matrices and Cyclodextrin: Melatonin Complexes

A series of hydrophilic matrix tablets was prepared and tested with respect to their ability to release the hormone melatonin in a controlled manner, in order to alleviate sleep onset and sleep maintenance dysfunctions. Besides the active ingredient, the tablets were comprised of combinations of the...

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Detalles Bibliográficos
Autores principales: Vlachou, Marilena, Papamichael, Marianna, Siamidi, Angeliki, Fragouli, Irene, Afroudakis, Pandelis A., Kompogennitaki, Rodanthi, Dotsikas, Yannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578031/
https://www.ncbi.nlm.nih.gov/pubmed/28788064
http://dx.doi.org/10.3390/ijms18081641

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